More evidence is needed to rate garlic for these uses.<\/p>\n

How does it work?<\/span><\/span><\/h3>\n

Garlic produces a chemical called allicin. This is what seems to make garlic work for certain conditions. Allicin also makes garlic smell. Some products are made \u201codorless\u201d by aging the garlic, but this process can also make the garlic less effective. It\u2019s a good idea to look for supplements that are coated (enteric coating) so they will dissolve in the intestine and not in the stomach.<\/p>\n

Are there safety concerns?<\/span><\/span><\/h3>\n

Garlic is LIKELY SAFE<\/strong> for most people when taken by mouth. Garlic can cause bad breath, a burning sensation in the mouth or stomach, heartburn, gas, nausea, vomiting, body odor, and diarrhea. These side effects are often worse with raw garlic. Garlic may also increase the risk of bleeding<\/span>. There have been reports of bleeding after surgery in people who have taken garlic. Asthma has been reported in people working with garlic, and other allergic reactions are possible.
\nWhen used on the skin, garlic is POSSIBLY UNSAFE<\/strong>. Using as a thick paste (poultice), garlic can cause damage to the skin that is similar to a burn.<\/p>\n

Special Precautions & Warnings:<\/h3>\n

Pregnancy and breast-feeding<\/strong>: Garlic is LIKELY SAFE<\/strong> in pregnancy when taken in the amounts normally found in food. Garlic is POSSIBLY UNSAFE<\/strong> when used in medicinal amounts in pregnancy and breast-feeding. There isn\u2019t enough reliable information about the safety of using garlic on the skin if you are pregnant or breast-feeding. Stay on the safe side, and avoid use.
\nChildren<\/strong>: Garlic is POSSIBLY SAFE<\/strong> when taken by mouth and appropriately for a short-term in children. But garlic is POSSIBLY UNSAFE<\/strong> when taken by mouth in large doses. Some sources suggest that high doses of garlic could be dangerous or even fatal to children; however, the reason for this warning is not known. There are no case reports available of significant adverse events or mortality in children associated with taking garlic by mouth.
\nBleeding disorder<\/strong>: Garlic, especially fresh garlic, might increase bleeding<\/span>.
\nStomach or digestion problems<\/strong>: Garlic can irritate the gastrointestinal (GI) tract. Use with caution if you have stomach or digestion problems.
\nSurgery<\/strong>: Garlic might prolong bleeding. Stop taking garlic at least two weeks before a scheduled surgery.<\/p>\n

Are there any interactions with medications?<\/p>\n

Birth control pills (Contraceptive drugs)<\/strong>
\nInteraction Rating = Moderate<\/strong> Be cautious with this combination.
\nTalk with your health provider.<\/p>\n

Some birth control pills contain estrogen. The body breaks down the estrogen in birth control pills to get rid of it. Garlic might increase the breakdown of estrogen. Taking garlic along with birth control pills might decrease the effectiveness of birth control pills. If you take birth control pills along with garlic, use an additional form of birth control such as a condom.
\nSome birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1\/35, Ortho-Novum 7\/7\/7), and others.<\/p>\n

Cyclosporine (Neoral, Sandimmune)<\/strong>
\nInteraction Rating = Moderate<\/strong> Be cautious with this combination.
\nTalk with your health provider.<\/p>\n

The affect of garlic preparations on cyclosporine may vary. Some garlic preparations containing allicin might decrease the effectiveness of cyclosporine. However, other garlic preparations containing alliin and alliinase may not. Until more is known about this possible interaction, don’t take garlic if you are taking cyclosporine.<\/p>\n

Isoniazid (INH, Nydrazid)<\/strong>
\nInteraction Rating = Major<\/strong> Do not take this combination.<\/span><\/p>\n

Garlic might reduce how much isoniazid (Nydrazid, INH) the body absorbs. This might decrease how well isoniazid (Nydrazid, INH) works. Don’t take garlic if you take isoniazid (Nydrazid, INH).<\/p>\n

Medications changed by the liver (Cytochrome P450 2E1 (CYP2E1) substrates)<\/strong>
\nInteraction Rating = Moderate<\/strong> Be cautious with this combination.
\nTalk with your health provider.<\/p>\n

Some medications are changed and broken down by the liver. Garlic oil might decrease how quickly the liver breaks down some medications. Taking garlic oil along with some medications that are changed by the liver can increase the effects and side effects of your medication. Before taking garlic oil, talk to your healthcare provider if you take any medications that are changed by the liver.
\nSome medications that are changed by the liver include acetaminophen, chlorzoxazone (Parafon Forte), ethanol, theophylline, and drugs used for anesthesia during surgery such as enflurane (Ethrane), halothane (Fluothane), isoflurane (Forane), and methoxyflurane (Penthrane).<\/p>\n

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)<\/strong>
\nInteraction Rating = Moderate<\/strong> Be cautious with this combination.
\nTalk with your health provider.<\/p>\n

Some medications are changed and broken down by the liver. Garlic might increase how quickly the liver breaks down some medications. Taking garlic along with some medications that are broken down by the liver can decrease the effectiveness of some medications. Before taking garlic, talk to your healthcare provider if you are taking any medications that are changed by the liver.
\nMedications that might be affected include certain heart medications called calcium channel blockers (diltiazem, nicardipine, verapamil), cancer drugs (etoposide, paclitaxel, vinblastine, vincristine, vindesine), fungus-fighting drugs (ketoconazole, itraconazole), glucocorticoids, alfentanil (Alfenta), cisapride (Propulsid), fentanyl (Sublimaze), lidocaine (Xylocaine), losartan (Cozaar), midazolam (Versed), and others.<\/p>\n

Medications that slow blood clotting (Anticoagulant \/ Antiplatelet drugs)<\/strong>
\nInteraction Rating = Moderate<\/strong> Be cautious with this combination.
\nTalk with your health provider.<\/p>\n

Garlic might slow blood clotting. Taking garlic along with medications that also slow clotting might increase the chances of bruising and bleeding.
\nSome medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.<\/p>\n

Medications used for HIV\/AIDS (Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs))<\/strong>
\nInteraction Rating = Major<\/strong> Do not take this combination.<\/p>\n

The body breaks down medications used for HIV\/AIDS to get rid of them. Garlic can increase how fast the body breaks down some medications for HIV\/AIDS. Taking garlic along with some medications used for HIV\/AIDS might decrease their effectiveness.
\nSome of these medications used for HIV\/AIDS include nevirapine (Viramune), delavirdine (Rescriptor), and efavirenz (Sustiva).<\/p>\n

Saquinavir (Fortovase, Invirase)<\/strong>
\nInteraction Rating = Major<\/strong> Do not take this combination.<\/p>\n

The body breaks down saquinavir (Fortovase, Invirase) to get rid of it. Garlic might increase how quickly the body breaks down saquinavir. Taking garlic along with saquinavir (Fortovase, Invirase) might decrease the effectiveness of saquinavir (Fortovase, Invirase).<\/p>\n

Warfarin (Coumadin)<\/strong>
\nInteraction Rating = Moderate<\/strong> Be cautious with this combination.
\nTalk with your health provider.<\/p>\n

Warfarin (Coumadin) is used to slow blood clotting. Garlic might increase the effectiveness of warfarin (Coumadin). Taking garlic along with warfarin (Coumadin) might increase the chances of bruising and bleeding. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.<\/p>\n

Are there any interactions with Herbs and Supplements?<\/p>\n

Fish oil (containing eicosapentaenoic acid (EPA))<\/strong><\/p>\n

Fish oil can slow blood clotting. Garlic can also slow clotting. Taken together, garlic and fish oil may increase the risk of bleeding in some people.<\/span><\/p>\n

Herbs and supplements that might slow blood clotting<\/strong><\/p>\n

Using garlic with other herbs that can slow blood clotting might increase the risk of bleeding in some people. These other herbs include angelica, clove, danshen, ginger, ginkgo, red clover, turmeric, vitamin E, willow, and others.<\/p>\n

Are there interactions with Foods?<\/p>\n

There are no known interactions with foods.<\/p>\n

What dose is used?<\/span><\/span><\/h3>\n

The following doses have been studied in scientific research:
\nBY MOUTH:<\/strong><\/p>\n

\n
• For high blood pressure:\n
  \n
  • Garlic extract 600-1200 mg divided and given three times daily.<\/li>\n
  • Standardized garlic powder extract containing 1.3% alliin content has been studied for this use.<\/li>\n
  • Aged garlic extract 600 mg to 7.2 grams per day has also been used. Aged garlic typically contains only 0.03% alliin.<\/li>\n
  • Fresh garlic 4 grams (approximately one clove) once daily has also been used. Fresh garlic typically contains 1% alliin.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n
    \n
    • For prevention of colon, rectal, and stomach cancer: fresh or cooked garlic 3.5-29 grams weekly.<\/li>\n<\/ul>\n

      APPLIED TO THE SKIN:<\/strong><\/p>\n

      \n
      • For fungal skin infections (ringworm, jock itch, athlete\u2019s foot): garlic ingredient ajoene as a 0.4% cream, 0.6% gel, and 1% gel applied twice daily for one week.<\/li>\n<\/ul>\n

        What other names is the product known by?<\/p>\n

        Aged Garlic Extract, Ail, Ajo, Allii Sativi Bulbus, Allium, Allium sativum, Camphor of the Poor, Clove Garlic, Da Suan, Garlic Clove, Garlic Oil, Lasun, Lasuna, Nectar of the Gods, Poor Man\u2019s Treacle, Rason, Rust Treacle, Stinking Rose.<\/p>\n

        Provided by
        \n4hourlife.com
        \nBased on
        \nNatural Medicines Comprehensive Database<\/em><\/p>\n

        From The 4-Hour Body<\/h2>\n

        GARLIC EXTRACT (ALLICIN POTENTIAL, S-ALLYL CYSTEINE)<\/h2>\n

        Garlic extract and its constituent parts have been used for applications ranging from cholesterol management to inhibiting lethal MRSA staph infections. Strangely, test subjects and I have had the best fat-loss results with extracts designed to deliver relatively high doses of allicin.\u00a0 Allicin, if delivered in a stable form, appears to have the ability to inhibit fat regain. The reason our results were \u201cstrange\u201d relates to the \u201cstable form\u201d bit.\u00a0 Most research indicates that allicin should have almost zero bioavailability more than six days after extraction from garlic cloves, particularly after exposure to stomach acid. Our confounding results could be due to a combination of other organic components, most notably one precursor to allicin: S-Allyl cysteine (alliin). S-Allyl cysteine exhibits outstanding oral bioavailability, near 100% in large mammals. Until further research concludes otherwise, I suggest using an aged-garlic extract (AGE) with high allicin potential that includes all constituent parts, including S-Allyl cysteine.\u00a0 If AGE isn\u2019t available, unaged garlic extract appears to work at slightly higher doses. I\u2019ve tried consuming it fresh, chomping on cloves, and it isn\u2019t kind to your digestive tract. If you are going the whole-food route, use it in your cooking to prevent stomach self-destruction. For precision and convenience, I use supplements to reach my target baseline in dosing, and I use extra garlic in food for delectable (but not necessary) insurance above that baseline.<\/p>\n

        Ferriss, Timothy (2010). The 4-Hour Body<\/p>\n

        Resources:<\/span> <\/span><\/h3>\n

        Nature’s Way Garlicin Enteric Coated Odor Free Tabs<\/a>\u00a0\u00a0(brand recommended by Tim from the 4-Hour Body)<\/p>\n

        <\/a><\/p>\n

        Natural Medicines Brand Evidence-based Rating (NMBER<\/a>)<\/p>\n

        <\/a><\/p>\n

        Ingredients:
        \nEach tablet contains: Garlic<\/a> bulb powder (providing allicin 3200 mcg) 350 mg. Other Ingredients: Cellulose, Aqueous Coating Solution, Xylitol, Modified Cellulose Gum, Stearic Acid, Silica.<\/p>\n","protected":false},"excerpt":{"rendered":"

        Note: The World Health Organization (WHO) 1999 monograph recommends 2-5 g of fresh garlic, 0.4-1.2 g of dried powder, 2-5 mg of oil, 300-1000 mg of extract, or other formulations corresponding to 2-5 mg allicin Garlic Extract\u00a0shows up in the 4-Hour Body as part of PAGG In the 4 Hour Body Tim Claims: \u201cAllicin, if […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"no_sidebars.php","meta":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/P1tiSR-E2","_links":{"self":[{"href":"https:\/\/www.4hourlife.com\/wp-json\/wp\/v2\/pages\/2482"}],"collection":[{"href":"https:\/\/www.4hourlife.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.4hourlife.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.4hourlife.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.4hourlife.com\/wp-json\/wp\/v2\/comments?post=2482"}],"version-history":[{"count":0,"href":"https:\/\/www.4hourlife.com\/wp-json\/wp\/v2\/pages\/2482\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.4hourlife.com\/wp-json\/wp\/v2\/media?parent=2482"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}