Acetaminophen (Tylenol, others)<\/h4>\n

Interaction Rating =\u00a0Minor<\/strong>\u00a0Be watchful with this combination.
\nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

The body breaks down acetaminophen (Tylenol, others) to get rid of it. Large amounts of vitamin C can decrease how quickly the body breaks down acetaminophen. It is not clear exactly when or if this interaction is a big concern.<\/p>\n\n\n\n

\n Aluminum<\/h4>\n Interaction Rating =\u00a0Moderate<\/strong>\u00a0Be cautious with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Aluminum is found in most antacids. Vitamin C can increase how much aluminum the body absorbs. But it isn’t clear if this interaction is a big concern. Take vitamin C two hours before or four hours after antacids.<\/p>\n\n\n\n \n Aspirin<\/h4>\n Interaction Rating =\u00a0Minor<\/strong>\u00a0Be watchful with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n The body breaks down aspirin to get rid of it. Large amounts of vitamin C might decrease the breakdown of aspirin. Decreasing the breakdown of aspirin might increase the effects and side effects of aspirin. Do not take large amounts of vitamin C if you take large amounts of aspirin.<\/p>\n\n\n\n \n Choline Magnesium Trisalicylate (Trilisate)<\/h4>\n Interaction Rating =\u00a0Minor<\/strong>\u00a0Be watchful with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Vitamin C might decrease how quickly the body gets rid of choline magnesium trisalicylate (Trilisate). But it is not clear if this interaction is a big concern.<\/p>\n\n\n\n \n Estrogens<\/h4>\n Interaction Rating =\u00a0Moderate<\/strong>\u00a0Be cautious with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n The body breaks down estrogens to get rid of them. Vitamin C might decrease how quickly the body gets rid of estrogens. Taking vitamin C along with estrogens might increase the effects and side effects of estrogens.<\/p>\n\n\n\n \n Fluphenazine (Prolixin)<\/h4>\n Interaction Rating =\u00a0Moderate<\/strong>\u00a0Be cautious with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Large amounts of vitamin C might decrease how much fluphenazine (Prolixin) is in the body. Taking vitamin C along with fluphenazine (Prolixin) might decrease the effectiveness of fluphenazine (Prolixin).<\/p>\n\n\n\n \n Medications for cancer (Chemotherapy)<\/h4>\n Interaction Rating =\u00a0Moderate<\/strong>\u00a0Be cautious with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Vitamin C is an antioxidant. There is some concern that antioxidants might decrease the effectiveness of some medications used for cancers. But it is too soon to know if this interaction occurs.<\/p>\n\n\n\n \n Medications used for HIV\/AIDS (Protease Inhibitors)<\/h4>\n Interaction Rating =\u00a0Moderate<\/strong>\u00a0Be cautious with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Taking large doses of vitamin C might reduce how much of some medications used for HIV\/AIDS stays in the body. This could decrease the effectiveness of some medications used for HIV\/AIDS.<\/p>\n Some of these medications used for HIV\/AIDS include amprenavir (Agenerase), nelfinavir (Viracept), ritonavir (Norvir), and saquinavir (Fortovase, Invirase).<\/p>\n\n\n\n \n Medications used for lowering cholesterol (Statins)<\/h4>\n Interaction Rating =\u00a0Moderate<\/strong>\u00a0Be cautious with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Taking vitamin C, beta-carotene, selenium, and vitamin E together might decrease the effectiveness of some medications used for lowering cholesterol. It is not known if vitamin C alone decreases the effectiveness of some medications used for lowering cholesterol.<\/p>\n Some medications used for lowering cholesterol include atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), and pravastatin (Pravachol).<\/p>\n\n\n\n \n Niacin<\/h4>\n Interaction Rating =\u00a0Moderate<\/strong>\u00a0Be cautious with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Taking vitamin C along with vitamin E, beta-carotene, and selenium might decrease some of the helpful effects of niacin. Niacin can increase the good cholesterol. Taking vitamin C along with these other vitamins might decrease the effectiveness of niacin for increasing good cholesterol.<\/p>\n\n\n\n \n Nicardipine (Cardene)<\/h4>\n Interaction Rating =\u00a0Minor<\/strong>\u00a0Be watchful with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Vitamin C is taken up by cells. Taking nicardipine (Cardene) along with vitamin C might decrease how much vitamin C is taken in by cells. The significance of this interaction is not clear.<\/p>\n\n\n\n \n Nifedipine<\/h4>\n Interaction Rating =\u00a0Minor<\/strong>\u00a0Be watchful with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Vitamin C is taken up by cells. Taking nifedipine (Adalat, Procardia) along with vitamin C might decrease how much vitamin C is taken in by cells. The significance of this interaction is not clear.<\/p>\n\n\n\n \n Salsalate (Disalcid)<\/h4>\n Interaction Rating =\u00a0Minor<\/strong>\u00a0Be watchful with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Vitamin C might decrease how quickly the body gets rid of salsalate (Disalcid). Taking vitamin C along with salsalate (Disalcid) might cause too much salsalate (Disalcid) in the body, and increase the effects and side effects of salsalate.<\/p>\n\n\n\n\n\n \n Warfarin (Coumadin)<\/h4>\n Interaction Rating =\u00a0Moderate<\/strong>\u00a0Be cautious with this combination. \nTalk with your health provider.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Warfarin (Coumadin) is used to slow blood clotting. Large amounts of vitamin C might decrease the effectiveness of warfarin (Coumadin). Decreasing the effectiveness of warfarin (Coumadin) might increase the risk of clotting. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.<\/td>\n<\/tr>\n Are there any interactions with Herbs and Supplements?<\/td>\n<\/tr>\n <\/td>\n \n\n\n\n \n Acerola<\/h4>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Acerola contains high levels of vitamin C. Don’t take large amounts of acerola along with vitamin C. This might give you too much vitamin C. Adults should not take more than 2000 mg vitamin C per day.<\/p>\n\n\n\n \n Cherokee rosehip<\/h4>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Cherokee rosehip contains high levels of vitamin C. Don’t take large amounts of Cherokee rosehip along with vitamin C. This might give you too much vitamin C. Adults should not take more than 2000 mg vitamin C per day.<\/p>\n\n\n\n \n Chromium<\/h4>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n There is some information that suggests that vitamin C increases chromium absorption. Don’t take large doses of chromium and vitamin C together. It isn’t known whether separating the doses by several hours avoids this interaction.<\/p>\n\n\n\n \n Copper<\/h4>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n High doses of vitamin C (1500 mg daily) can decrease copper levels in the blood in young men. Researchers aren’t sure why this happens, but it may be that the acid in vitamin C converts copper to a form that doesn’t pass easily from food in the intestine to the bloodstream. Or it may be that vitamin C somehow causes the body to use up copper in the blood. This interaction probably isn’t important except in people whose dietary levels of copper is low.<\/p>\n\n\n\n \n Grape<\/h4>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n These is early evidence that people with high blood pressure who take both vitamin C 500 mg\/day plus grape seed polyphenols 1000 mg\/day have significantly increased blood pressure. Researchers aren’t sure why this happens.<\/p>\n\n\n\n \n Iron<\/h4>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Vitamin C increases the absorption of iron when taken at the same time. Taking a vitamin C supplement to improve absorption of iron from the diet or from supplements probably isn’t necessary for most people, especially if their diet contains plenty of vitamin C.<\/p>\n\n\n\n \n Rosehip<\/h4>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Rosehip contains high levels of vitamin C. Don’t take large amounts of rosehip along with vitamin C. This might give you too much vitamin C. Adults should not take more than 2000 mg vitamin C per day.<\/p>\n\n\n\n\n\n\n\n\n\n \n Vitamin B12<\/h4>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Early research suggests that vitamin C supplements can destroy vitamin B12 that comes from the diet. However, other ingredients in food, such as iron and nitrates, might counteract this effect. Researchers aren’t sure how important this interaction is, but it can likely be avoided if vitamin C supplements are taken at least 2 hours after meals.<\/td>\n<\/tr>\n Are there interactions with Foods?<\/td>\n<\/tr>\n <\/td>\n There are no known interactions with foods.<\/td>\n<\/tr>\n What dose is used?<\/td>\n<\/tr>\n <\/td>\n The following doses have been studied in scientific research:BY MOUTH<\/strong>:<\/p>\n \n For scurvy: 100-250 mg once or twice daily for several days.<\/li>\n For treating the common cold: 1-3 grams daily.<\/li>\n For preventing kidney damage related to contrast media used during diagnostic tests: vitamin C 3 grams is given before coronary angiography and then 2 grams is given after the procedure in the evening and again the following morning.<\/li>\n For slowing progression of hardening of the arteries: slow-release vitamin C 250 mg in combination with 91 mg (136 IU) of vitamin E twice daily for up to 6 years.<\/li>\n For tyrosinemia in premature infants on high protein diets: 100 mg of vitamin C.<\/li>\n For reducing protein in the urine of patients with type 2 diabetes: vitamin C 1250 mg with vitamin E 680 IU daily for 4 weeks.<\/li>\n For preventing complex regional pain syndrome in patients with wrist fractures, vitamin C 500 mg daily for 50 days.<\/li>\n<\/ul>\n The daily recommended dietary allowances (RDAs) are: Infants 0 to 12 months, human milk content (older recommendations specified 30-35 mg); Children 1 to 3 years, 15 mg; Children 4 to 8 years, 25 mg; Children 9 to 13 years, 45 mg; Adolescents 14 to 18 years, 75 mg for boys and 65 mg for girls; Adults age 19 and greater, 90 mg for men and 75 mg for women; Pregnancy and Lactation: age 18 or younger, 115 mg; ages 19 to 50 years 120 mg. People who use tobacco should take an additional 35 mg per day. \nDo not take more than the following amounts of vitamin C: 400 mg per day for children ages 1 to 3 years, 650 mg per day for children 4 to 8 years, 1200 mg per day for children 9 to 13 years, and 1800 mg per day for adolescents and pregnant and breast-feeding women 14 to 18 years, and 2000 mg per day for adults and pregnant and lactating women.<\/p>\n APPLIED TO THE SKIN<\/strong>:<\/p>\n \n Most topical preparations used for aged or wrinkled skin are applied daily. Studies have used creams containing 5% to 10% vitamin C. In one study a specific vitamin C formulation (Cellex-C High Potency Serum) used 3 drops applied daily to areas of facial skin. Don\u2019t apply vitamin C preparations to the eye or eyelids. Also avoid contact with hair or clothes. It can cause discoloration.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n What other names is the product known by?<\/td>\n<\/tr>\n <\/td>\n Acide Ascorbique, Acide C\u00e9vitamique, Acide Iso-Ascorbique, Acide L-Ascorbique, Acido Ascorbico, Antiscorbutic Vitamin, Ascorbate, Ascorbate de Calcium, Ascorbate de Sodium, Ascorbic acid, Ascorbyl Palmitate, Calcium Ascorbate, Cevitamic Acid, Iso-Ascorbic Acid, L-Ascorbic Acid, Magnesium Ascorbate, Palmitate d’Ascorbyl, Selenium Ascorbate, Sodium Ascorbate, Vitamina C, Vitamine Antiscorbutique, Vitamine C.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Resources:<\/h3>\n